Tg(TG-HPV16E6E7)1Py
Transgene Detail
|
|
| Symbol: |
Tg(TG-HPV16E6E7)1Py |
| Name: |
transgene insertion 1, Yvonne Paterson |
| MGI ID: |
MGI:3716115 |
| Synonyms: |
E6/E7 |
| Transgene: |
Tg(TG-HPV16E6E7)1Py Location: unknown
|
| Alliance: |
Tg(TG-HPV16E6E7)1Py page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgene contains the bovine thyroglobulin promoter, a rabbit beta-globin intron, the E6 and E7 protein-coding genes of human papillomavirus 16 (HPV16) and a polyadenylation signal. Real-time PCR analysis detected E7 mRNA in the thyroid glands and in medullary epithelial cells of the thymi, but not in liver, spleen or whole thymi of transgenic mice. E6 expression was not examined.
(J:121727)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:121727 Souders NC, et al., Listeria-based vaccines can overcome tolerance by expanding low avidity CD8+ T cells capable of eradicating a solid tumor in a transgenic mouse model of cancer. Cancer Immun. 2007;7:2 |
| All: |
1 reference(s) |
|
Analysis Tools
