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Tg(282M13-Ank*M48T)1Kng
Transgene Detail
Summary
Symbol: Tg(282M13-Ank*M48T)1Kng
Name: transgene insertion 1, David M Kingsley
MGI ID: MGI:3715536
Synonyms: AnkM48T, BAC-AnkM48T
Transgene: Tg(282M13-Ank*M48T)1Kng  Location: unknown  
Alliance: Tg(282M13-Ank*M48T)1Kng page
Transgene
origin
Strain of Origin:  FVB/N or (C57BL/6 x CBA)F1/J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(282M13-Ank*M48T)1Kng expresses 1 gene
 
Mutation detailsA point mutation was made in the Ank gene contained within Tg(282M13)1Kng converting a methionine to a threonine at amino acid position 48. This mutation is commonly found in patients with familial chondrocalcinosis (CCAL2) and has wild-type levels of PPi-transport in vitro. (J:122441)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Transgene was inserted into the nuclei of fertilized eggs from FVB/N or (C57BL/6 x CBA)F1/J mice.
References
Original:  J:122441 Gurley KA, et al., Biochemical and genetic analysis of ANK in arthritis and bone disease. Am J Hum Genet. 2006 Dec;79(6):1017-29
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory