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Card9tm1Tks
Targeted Allele Detail
Nomenclature
Symbol: Card9tm1Tks
Name: caspase recruitment domain family, member 9; targeted mutation 1, Takashi Saito
MGI ID: MGI:3715521
Synonyms: Card9-
Gene: Card9  Location: Chr2:26352176-26360918 bp, - strand  Genetic Position: Chr2, 18.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122394
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2, including the ATG start codon and the CARD-encoding region, was replaced with a neomycin resistance cassette. Absence of protein was confirmed by immunoblot analysis. (J:122394)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Card9 Mutation:  13 strains or lines available
References
Original:  J:122394 Hara H, et al., The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors. Nat Immunol. 2007 Jun;8(6):619-29
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory