Kiss1tm1Coll
Targeted Allele Detail
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Symbol: |
Kiss1tm1Coll |
Name: |
KiSS-1 metastasis-suppressor; targeted mutation 1, William H Colledge |
MGI ID: |
MGI:3715520 |
Synonyms: |
Kiss1tm1Ptl |
Gene: |
Kiss1 Location: Chr1:133309827-133329722 bp, + strand Genetic Position: Chr1, 57.91 cM
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Reproductive system defects in female Kiss1tm1Coll/Kiss1tm1Coll mice.
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:122381
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Parent Cell Line: |
CCB (ES Cell)
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Strain of Origin: |
129S/SvEv-Gpi1c |
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector was designed to replace both coding exons with an IRES-lacZ-neo cassette. The absence of transcript and protein was confirmed in mutant mice.
(J:122381)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Kiss1 Mutation: |
10 strains or lines available
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Original: |
J:122381 d'Anglemont de Tassigny X, et al., Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10714-9 |
All: |
8 reference(s) |
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