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Syt5tm2.1Sud
Targeted Allele Detail
Nomenclature
Symbol: Syt5tm2.1Sud
Name: synaptotagmin V; targeted mutation 2.1, Thomas C Sudhof
MGI ID: MGI:3715454
Synonyms: S9X, Syt9tm1.1Sud
Gene: Syt5  Location: Chr7:4539765-4547541 bp, - strand  Genetic Position: Chr7, 2.62 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122459
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre-mediated recombination was used to remove exon 2 from the tm1 allele to create a null allele. The absence of protein product was confirmed by western blot analysis. (J:122459)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syt5 Mutation:  11 strains or lines available
References
Original:  J:122459 Xu J, et al., Synaptotagmin-1, -2, and -9: Ca(2+) sensors for fast release that specify distinct presynaptic properties in subsets of neurons. Neuron. 2007 May 24;54(4):567-81
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory