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Bmp4tm3.2Blh
Targeted Allele Detail
Nomenclature
Symbol: Bmp4tm3.2Blh
Name: bone morphogenetic protein 4; targeted mutation 3.2, Brigid L Hogan
MGI ID: MGI:3715255
Synonyms: Bmp4delta-lacZ
Gene: Bmp4  Location: Chr14:46383520-46390669 bp, - strand  Genetic Position: Chr14, 23.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122530
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 3 and 4 were removed by cre-mediated recombination to create a loss of function allele. (J:122530)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp4 Mutation:  16 strains or lines available
References
Original:  J:122530 Michos O, et al., Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development. 2007 Jul;134(13):2397-405
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory