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Sun1tm1Mhan
Targeted Allele Detail
Nomenclature
Symbol: Sun1tm1Mhan
Name: Sad1 and UNC84 domain containing 1; targeted mutation 1, Min Han
MGI ID: MGI:3715140
Synonyms: Sun1-, Sun1(delta ex10-13)
Gene: Sun1  Location: Chr5:139200637-139249840 bp, + strand  Genetic Position: Chr5, 78.12 cM, cytoband G1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122602
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons encoding all three putative transmembrane domains of SUN1 (exons 10-13) were replaced by a neomycin resistance gene. RT-PCR confirmed absence of normal mRNA transcripts in mutant testis and muscle. (J:122602)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sun1 Mutation:  37 strains or lines available
References
Original:  J:122602 Ding X, et al., SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell. 2007 Jun;12(6):863-72
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory