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Targeted Allele Detail
Symbol: Ubctm1Rrk
Name: ubiquitin C; targeted mutation 1, Ron R Kopito
MGI ID: MGI:3715099
Synonyms: UbC-, UbCGFP-Puro, UbcGt(GFP-Puro)1Rrk, Ubctm11Rrk
Gene: Ubc  Location: Chr5:125385965-125390202 bp, - strand  Genetic Position: Chr5, 64.18 cM
Germline Transmission:  Earliest citation of germline transmission: J:122574
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA floxed GFP and puro cassette is used to replace the entire coding region creating a null allele. This cassette can be removed with Cre recombination without any effect. (J:122574)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ubc Mutation:  8 strains or lines available
Original:  J:122574 Ryu KY, et al., The mouse polyubiquitin gene UbC is essential for fetal liver development, cell-cycle progression and stress tolerance. EMBO J. 2007 Jun 6;26(11):2693-706
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory