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Lmx1btm1Witz
Targeted Allele Detail
Nomenclature
Symbol: Lmx1btm1Witz
Name: LIM homeobox transcription factor 1 beta; targeted mutation 1, Ralph Witzgall
MGI ID: MGI:3714802
Synonyms: Lmxb1lox
Gene: Lmx1b  Location: Chr2:33560965-33640511 bp, - strand  Genetic Position: Chr2, 22.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122505
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted into introns 4 and 6, flanking sequence that encodes the homeodomain. (J:122505)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmx1b Mutation:  1 strain or line available
References
Original:  J:122505 Suleiman H, et al., The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Dev Biol. 2007 Apr 15;304(2):701-12
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory