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Cby1tm1Ktkm
Targeted Allele Detail
Nomenclature
Symbol: Cby1tm1Ktkm
Name: chibby family member 1, beta catenin antagonist; targeted mutation 1, Ken-Ichi Takemaru
MGI ID: MGI:3714454
Synonyms: Cby-
Gene: Cby1  Location: Chr15:79659227-79667660 bp, + strand  Genetic Position: Chr15, 37.84 cM, cytoband E2
Small size and postnatal lethality of Cby1tm1Ktkm/Cby1tm1Ktkm mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122334
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The coding region was replaced with a neo cassette. (J:147413)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cby1 Mutation:  8 strains or lines available
References
Original:  J:122334 Li FQ, et al., Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling. Mol Cell Biol. 2007 Jun;27(12):4347-54
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory