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Slc32a1tm1Yyan
Targeted Allele Detail
Nomenclature
Symbol: Slc32a1tm1Yyan
Name: solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 1, Yuchio Yanagawa
MGI ID: MGI:3714155
Synonyms: VGAT-
Gene: Slc32a1  Location: Chr2:158610767-158615748 bp, + strand  Genetic Position: Chr2, 78.72 cM, cytoband H1-3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122360
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. Exons 2 and 3 were removed by subsequent cre-mediated recombination. Absence of protein was confirmed by Western blot analysis. (J:122055, J:122360)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc32a1 Mutation:  14 strains or lines available
References
Original:  J:122360 Saito K, Generation and analysis of vesicular GABA transporter knockout mouse. Neuroscience. 2006;:abstract
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory