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Fndc3aGt(RRP208)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Fndc3aGt(RRP208)Byg
Name: fibronectin type III domain containing 3A; gene trap RRP208, BayGenomics
MGI ID: MGI:3713800
Synonyms: Fndc3aRRP208
Gene: Fndc3a  Location: Chr14:72537946-72710003 bp, - strand  Genetic Position: Chr14, 37.62 cM
Mutation
origin
Mutant Cell Line:  RRP208
Germline Transmission:  Earliest citation of germline transmission: J:119576
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsThe pGT0Lxf vector was integrated into intron 3. The integration was predicted to cause loss of full-length protein and result in production of a fusion product composed of the first 57 amino acids fused to the betagalactosidase-neomycin gene. (J:119576)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fndc3a Mutation:  14 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:119576 Obholz KL, et al., FNDC3A is required for adhesion between spermatids and Sertoli cells. Dev Biol. 2006 Oct 15;298(2):498-513
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory