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Targeted Allele Detail
Symbol: Dyrk4tm1Dgen
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; targeted mutation 1, Deltagen
MGI ID: MGI:3713116
Synonyms: Dyrk-
Gene: Dyrk4  Location: Chr6:126876020-126921839 bp, - strand  Genetic Position: Chr6, 61.92 cM
Germline Transmission:  Earliest citation of germline transmission: J:119704
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 6 and 7, containing parts of the ATP binding domain, were replaced by a neo-lacZ cassette. Northern blot and RT-PCR confirmed absence of transcript in mutants. (J:119704)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dyrk4 Mutation:  12 strains or lines available
Original:  J:119704 Sacher F, et al., The expression of the testis-specific Dyrk4 kinase is highly restricted to step 8 spermatids but is not required for male fertility in mice. Mol Cell Endocrinol. 2007 Mar 15;267(1-2):80-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.06
The Jackson Laboratory