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Engtm2.1Hma
Targeted Allele Detail
Nomenclature
Symbol: Engtm2.1Hma
Name: endoglin; targeted mutation 2.1, Helen M Arthur
MGI ID: MGI:3712802
Synonyms: Eng2f
Gene: Eng  Location: Chr2:32646595-32682669 bp, + strand  Genetic Position: Chr2, 22.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121898
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 5 and 6 remained flanked by loxp sites following the removal of a floxed neo by cre mediated recombination. (J:121898)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eng Mutation:  34 strains or lines available
References
Original:  J:121898 Allinson KR, et al., Generation of a floxed allele of the mouse endoglin gene. Genesis. 2007 Jun;45(6):391-5
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory