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Thbdtm2Emc
Targeted Allele Detail
Nomenclature
Symbol: Thbdtm2Emc
Name: thrombomodulin; targeted mutation 2, Edward M Conway
MGI ID: MGI:3712468
Synonyms: TMLeDneo
Gene: Thbd  Location: Chr2:148404466-148408188 bp, - strand  Genetic Position: Chr2, 73.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118000
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thbd Mutation:  1 strain or line available
References
Original:  J:118000 Conway EM, et al., The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J Exp Med. 2002 Sep 2;196(5):565-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory