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Ccl7tm1Ifc
Targeted Allele Detail
Nomenclature
Symbol: Ccl7tm1Ifc
Name: chemokine (C-C motif) ligand 7; targeted mutation 1, Israel F Charo
MGI ID: MGI:3712065
Synonyms: Mcp-3-
Gene: Ccl7  Location: Chr11:82045712-82047525 bp, + strand  Genetic Position: Chr11, 49.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121281
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector containing a neomycin resistance cassette was inserted to replace the coding sequence. (J:121281)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccl7 Mutation:  6 strains or lines available
References
Original:  J:121281 Tsou CL, et al., Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest. 2007 Apr;117(4):902-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory