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Ets1tm1.1Dds
Targeted Allele Detail
Nomenclature
Symbol: Ets1tm1.1Dds
Name: E26 avian leukemia oncogene 1, 5' domain; targeted mutation 1.1, Demetri D Spyropoulos
MGI ID: MGI:3711457
Synonyms: Ets1deltaVII
Gene: Ets1  Location: Chr9:32636221-32757820 bp, + strand  Genetic Position: Chr9, 17.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121460
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon VII was removed via transient cre expression in ES cells. Western blot confirmed absence of expression of the VII isoform. (J:121460)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ets1 Mutation:  8 strains or lines available
Notes
ES cell line = TC1-10.
References
Original:  J:121460 Higuchi T, et al., Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice. Mol Cell Biol. 2007 May;27(9):3353-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory