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Targeted Allele Detail
Symbol: Cxadrtm1.1Mds
Name: coxsackie virus and adenovirus receptor; targeted mutation 1.1, Michael D Schneider
MGI ID: MGI:3711226
Synonyms: Car-
Gene: Cxadr  Location: Chr16:78301496-78359785 bp, + strand  Genetic Position: Chr16, 45.28 cM, cytoband C
Germline Transmission:  Earliest citation of germline transmission: J:121400
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsExon 2 was removed via cre mediated recombination in the germline. Absence of transcript and protein were demonstrated by RT-PCR and western blot, respectively. (J:121400)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxadr Mutation:  2 strains or lines available
Original:  J:121400 Chen JW, et al., Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves. Circ Res. 2006 Apr 14;98(7):923-30
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
The Jackson Laboratory