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Nol3tm1Rvh
Targeted Allele Detail
Nomenclature
Symbol: Nol3tm1Rvh
Name: nucleolar protein 3 (apoptosis repressor with CARD domain); targeted mutation 1, Rudiger von Harsdorf
MGI ID: MGI:3711185
Synonyms: Arc-
Gene: Nol3  Location: Chr8:105276145-105281939 bp, + strand  Genetic Position: Chr8, 53.04 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121501
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2, 3 and 4 were replaced with a neomycin resistance cassette. (J:121501)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nol3 Mutation:  7 strains or lines available
References
Original:  J:121501 Donath S, et al., Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation. 2006 Mar 7;113(9):1203-12
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory