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Fh1tm1.1Pjp
Targeted Allele Detail
Nomenclature
Symbol: Fh1tm1.1Pjp
Name: fumarate hydratase 1; targeted mutation 1.1, Patrick J Pollard
MGI ID: MGI:3711129
Synonyms: Fh1-
Gene: Fh1  Location: Chr1:175600374-175625635 bp, - strand  Genetic Position: Chr1, 81.58 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120969
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMice with the floxed Fh1 allele were crossed with cre-expressing mice to delete the floxed exons 2 and 3. (J:120969)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fh1 Mutation:  23 strains or lines available
References
Original:  J:120969 Pollard PJ, et al., Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Cancer Cell. 2007 Apr;11(4):311-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory