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Rbbp6tm1Xya
Targeted Allele Detail
Nomenclature
Symbol: Rbbp6tm1Xya
Name: retinoblastoma binding protein 6; targeted mutation 1, Xiao Yang
MGI ID: MGI:3711066
Synonyms: Pact-
Gene: Rbbp6  Location: Chr7:122965686-123002557 bp, + strand  Genetic Position: Chr7, 67.42 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121586
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The two exons comprising the Trp53 binding domain were replaced with a neo cassette. (J:121586)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbbp6 Mutation:  17 strains or lines available
References
Original:  J:121586 Li L, et al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory