About   Help   FAQ
Rbbp6tm1Xya
Targeted Allele Detail
Nomenclature
Symbol: Rbbp6tm1Xya
Name: retinoblastoma binding protein 6, ubiquitin ligase; targeted mutation 1, Xiao Yang
MGI ID: MGI:3711066
Synonyms: Pact-
Gene: Rbbp6  Location: Chr7:122965686-123002557 bp, + strand  Genetic Position: Chr7, 67.42 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121586
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The two exons comprising the Trp53 binding domain were replaced with a neo cassette. (J:121586)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbbp6 Mutation:  22 strains or lines available
References
Original:  J:121586 Li L, et al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/15/2017
MGI 6.10
The Jackson Laboratory