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Targeted Allele Detail
Symbol: G6pc3tm1Jyc
Name: glucose 6 phosphatase, catalytic, 3; targeted mutation 1, Janice Y Chou
MGI ID: MGI:3710232
Synonyms: G6Pase-beta-, G6pc3-
Gene: G6pc3  Location: Chr11:102189699-102194081 bp, + strand  Genetic Position: Chr11, 65.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:120741
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to replace exons 3-5 with a floxed neomycin resistance cassette. Western blot confirmed absence of protein in mutant brain, muscle and testis. (J:120741)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any G6pc3 Mutation:  3 strains or lines available
Original:  J:120741 Cheung YY, et al., Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase-beta. J Clin Invest. 2007 Mar;117(3):784-93
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory