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Targeted Allele Detail
Symbol: Plxdc1tm1Matl
Name: plexin domain containing 1; targeted mutation 1, Marc Tessier-Lavigne
MGI ID: MGI:3709571
Synonyms: Plxdc1-Betageo
Gene: Plxdc1  Location: Chr11:97923238-97986444 bp, - strand  Genetic Position: Chr11, 61.31 cM
Germline Transmission:  Earliest citation of germline transmission: J:121225
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA targeted trap vector was fused to gene-specific homology arms such that homologous recombination was used to insert the vector into intron 11 of the locus. This vector contains a splice acceptor, betagalactosidase, IRES-PLAP and polyA signal. (J:121225)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plxdc1 Mutation:  7 strains or lines available
Original:  J:121225 Friedel RH, et al., Gene targeting using a promoterless gene trap vector ('targeted trapping') is an efficient method to mutate a large fraction of genes. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13188-93
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory