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Transgene Detail
Symbol: Tg(Alb-F5)2Dgi
Name: transgene insertion 2, David Ginsburg
MGI ID: MGI:3709371
Synonyms: AlbfvC
Transgene: Tg(Alb-F5)2Dgi  Location: unknown  
Strain of Origin:  (C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(Alb-F5)2Dgi expresses 1 gene
Mutation detailsThe transgenic construct has the mouse albumin promoter driving expression of the murine F5 (FV) gene including the entire coding sequence. An IRES-EGFP cassette with a bacterial gene wasinserting after the F5 coding sequence. A chimeric intron with optimized splice signals was introduced upstream of the F5 cDNA enhance gene expression. Transgenic F5 expression is restricted to the liver. EGFP expression is not detected. (J:86150)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:86150 Sun H, et al., The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood. 2003 Oct 15;102(8):2856-61
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory