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Transgene Detail
Symbol: Tg(Npy-hrGFP)1Lowl
Name: transgene insertion 1, Bradford B Lowell
MGI ID: MGI:3709190
Synonyms: NPY-GFP, Npy-hrGFP
Transgene: Tg(Npy-hrGFP)1Lowl  Location: unknown  
Strain of Origin:  FVB
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsA bacterial artificial chromosome (BAC) was modified by inserting a humanized Renilla GFP (hrGFP, Stratagene) sequence into the translational start site of the mouse neuropeptide Y (Npy) gene. Correctly transformed and targeted bacteria were used to isolate the ~200 kb transgenic construct (called "NPY-GFP"). This NPY-GFP transgene was used for pronuclear injection into fertilized one-cell stage FVB embryos. Founder line 1 showing germline transmission was established. Brain tissues show GFP fluorescence when exposed to UV light. (J:120993)
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Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:120993 Lowell BB, Generation of transgenic reporter mice with umanized Renilla GFP under control of the NPY promoter. MGI Direct Data Submission. 2007;
All:  105 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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