Lrp4^mte
Chemically induced Allele Detail

Summary

• Symbol: Lrp4^mte
• Name: low density lipoprotein receptor-related protein 4; mitaine
• MGI ID: MGI:3707726
• Gene: Lrp4 Location: Chr2:91287856-91344124 bp, + strand Genetic Position: Chr2, 50.63 cM
• Alliance: Lrp4^mte page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: This allele is a missense mutation in aspartate 1436 that converts it to a glycine and is located in the C-terminal YWTD domain. (J:119654)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrp4 Mutation: 97 strains or lines available

References

• Original: J:119654 Weatherbee SD, et al., LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development. 2006 Dec;133(24):4993-5000
• All: 3 reference(s)