Drd1^tm2Jcd
Targeted Allele Detail

Summary

• Symbol: Drd1^tm2Jcd
• Name: dopamine receptor D1; targeted mutation 2, John Drago
• MGI ID: MGI:3707260
• Synonyms: HZ^non-ac
• Gene: Drd1 Location: Chr13:54205202-54209677 bp, - strand Genetic Position: Chr13, 28.4 cM
• Alliance: Drd1^tm2Jcd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120582
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a transcriptionally silenced attenuated diphtheria toxin (tox-176) gene into the locus. The tox-176 gene was preceeded by a floxed neo-stop cassette. (J:120582)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Drd1 Mutation: 68 strains or lines available

References

• Original: J:120582 Drago J, et al., Targeted expression of a toxin gene to D1 dopamine receptor neurons by cre-mediated site-specific recombination. J Neurosci. 1998 Dec 1;18(23):9845-57
• All: 6 reference(s)