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Drd1tm2Jcd
Targeted Allele Detail
Nomenclature
Symbol: Drd1tm2Jcd
Name: dopamine receptor D1; targeted mutation 2, John Drago
MGI ID: MGI:3707260
Synonyms: HZnon-ac
Gene: Drd1  Location: Chr13:54051183-54055658 bp, - strand  Genetic Position: Chr13, 28.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120582
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a transcriptionally silenced attenuated diphtheria toxin (tox-176) gene into the locus. The tox-176 gene was preceeded by a floxed neo-stop cassette. (J:120582)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Drd1 Mutation:  52 strains or lines available
References
Original:  J:120582 Drago J, et al., Targeted expression of a toxin gene to D1 dopamine receptor neurons by cre-mediated site-specific recombination. J Neurosci. 1998 Dec 1;18(23):9845-57
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory