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Bag6tm1Pmc
Targeted Allele Detail
Nomenclature
Symbol: Bag6tm1Pmc
Name: BCL2-associated athanogene 6; targeted mutation 1, Peter J McKinnon
MGI ID: MGI:3705047
Synonyms: BAT3-, Scythe-
Gene: Bag6  Location: Chr17:35135178-35147320 bp, + strand  Genetic Position: Chr17, 18.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119857
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAlmost the entire open reading frame was replaced with a neo cassette. The absence of the 130KDa protein was confirmed by western blot analysis of homozygous embryo fibroblasts. (J:119857)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bag6 Mutation:  16 strains or lines available
References
Original:  J:119857 Desmots F, et al., The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol. 2005 Dec;25(23):10329-37
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory