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Prdm1tm2Masu
Targeted Allele Detail
Summary
Symbol: Prdm1tm2Masu
Name: PR domain containing 1, with ZNF domain; targeted mutation 2, M Azim Surani
MGI ID: MGI:3703794
Synonyms: Blimp1fl, Blimp1 loxP
Gene: Prdm1  Location: Chr10:44313173-44404497 bp, - strand  Genetic Position: Chr10, 23.24 cM
Alliance: Prdm1tm2Masu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99994
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo selection casset and an additional loxP site flanked exon5. The Neo cassette was then removed by Cre mediated excision. (J:99994)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prdm1 Mutation:  48 strains or lines available
References
Original:  J:99994 Ohinata Y, et al., Blimp1 is a critical determinant of the germ cell lineage in mice. Nature. 2005 Jul 14;436(7048):207-13
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory