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Rictortm1.1Mgn
Targeted Allele Detail
Summary
Symbol: Rictortm1.1Mgn
Name: RPTOR independent companion of MTOR, complex 2; targeted mutation 1.1, Mark A Magnuson
MGI ID: MGI:3703321
Synonyms: ricEx3cond
Gene: Rictor  Location: Chr15:6737860-6829882 bp, + strand  Genetic Position: Chr15, 3.25 cM, cytoband A1
Alliance: Rictortm1.1Mgn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119564
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsUpon expression of Flp recombinase, the lacZ-pA is removed from the locus, leaving a single frt site and exon 3 flanked by loxP sites. (J:119564)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rictor Mutation:  92 strains or lines available
References
Original:  J:119564 Shiota C, et al., Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell. 2006 Oct;11(4):583-9
All:  55 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/26/2022
MGI 6.22
The Jackson Laboratory