Smad2tm1.2Epb
Targeted Allele Detail
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Symbol: |
Smad2tm1.2Epb |
Name: |
SMAD family member 2; targeted mutation 1.2, Erwin P Bottinger |
MGI ID: |
MGI:3703161 |
Synonyms: |
Smad2neodeltaex2 |
Gene: |
Smad2 Location: Chr18:76374651-76444034 bp, + strand Genetic Position: Chr18, 51.42 cM
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Alliance: |
Smad2tm1.2Epb page
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Germline Transmission: |
Earliest citation of germline transmission:
J:119642
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Parent Cell Line: |
WW6 (ES Cell)
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Strain of Origin: |
STOCK 129/Sv and C57BL/6J and SJL
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele contains a floxed pgk-neo in place of exon 2. Exon 2, which contains the ATG, was removed following in vivo cre-mediated recombination by crossing with cre mice.
(J:119642)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Smad2 Mutation: |
50 strains or lines available
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Original: |
J:119642 Ju W, et al., Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol. 2006 Jan;26(2):654-67 |
All: |
1 reference(s) |
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