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Nfkbidtm1Ktak
Targeted Allele Detail
Nomenclature
Symbol: Nfkbidtm1Ktak
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta; targeted mutation 1, Kiyoshi Takeda
MGI ID: MGI:3702939
Synonyms: IkappaBNS-
Gene: Nfkbid  Location: Chr7:30421732-30428746 bp, + strand  Genetic Position: Chr7, 17.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113334
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette was inserted to replace a fragment containing exons 5-8. Northern blot confirmed inactivation of the locus. (J:113334)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfkbid Mutation:  14 strains or lines available
References
Original:  J:113334 Kuwata H, et al., IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity. 2006 Jan;24(1):41-51
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory