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Targeted Allele Detail
Symbol: Tcrbtm1Slek
Name: T cell receptor beta chain; targeted mutation 1, Barry P Sleckman
MGI ID: MGI:3702573
Synonyms: Jbeta1omega
Gene: Tcrb  Location: Chr6:40891296-41558371 bp, + strand  Genetic Position: Chr6, cytoband A-C
Germline Transmission:  Earliest citation of germline transmission: J:119552
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe locus was interrupted by the replacement of the Dbeta2-Jbeta2 gene cluster with a loxP site. Gene segment rearrangements on this allele are restricted to the Dbeta1-Jbeta1 gene segment cluster, which contains one Dbeta (Dbeta1) and six Jbeta (Jbeta1.1-Jbeta1.6) gene segments. (J:119552)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcrb Mutation:  81 strains or lines available
Original:  J:119552 Bassing CH, et al., Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. Nature. 2000 Jun 1;405(6786):583-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.08
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