About   Help   FAQ
Tcrbtm1Slek
Targeted Allele Detail
Nomenclature
Symbol: Tcrbtm1Slek
Name: T cell receptor beta chain; targeted mutation 1, Barry P Sleckman
MGI ID: MGI:3702573
Synonyms: Jbeta1omega
Gene: Tcrb  Location: Chr6:40891296-41558371 bp, + strand  Genetic Position: Chr6, cytoband A-C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119552
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe locus was interrupted by the replacement of the Dbeta2-Jbeta2 gene cluster with a loxP site. Gene segment rearrangements on this allele are restricted to the Dbeta1-Jbeta1 gene segment cluster, which contains one Dbeta (Dbeta1) and six Jbeta (Jbeta1.1-Jbeta1.6) gene segments. (J:119552)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcrb Mutation:  82 strains or lines available
References
Original:  J:119552 Bassing CH, et al., Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule. Nature. 2000 Jun 1;405(6786):583-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/19/2017
MGI 6.10
The Jackson Laboratory