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Smad9tm1Rob
Targeted Allele Detail
Nomenclature
Symbol: Smad9tm1Rob
Name: SMAD family member 9; targeted mutation 1, Elizabeth J Robertson
MGI ID: MGI:3701868
Synonyms: Smad8.LacZ
Gene: Smad9  Location: Chr3:54755582-54801257 bp, + strand  Genetic Position: Chr3, 25.62 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119296
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA LacZ cassette was inserted into the AUG-containing exon 2, disrupting endogenous coding sequence and creating a null allele. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter. (J:119296)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 65 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Smad9 Mutation:  22 strains or lines available
References
Original:  J:119296 Arnold SJ, et al., Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol. 2006 Aug 1;296(1):104-18
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory