Tg(Tcra3A)1Skd
Transgene Detail

Summary

• Symbol: Tg(Tcra3A)1Skd
• Name: transgene insertion 1, Syamal Datta
• MGI ID: MGI:3701792
• Synonyms: 3A TCR alpha-chain, Tg(Tcra-V19.1)1Skd
• Transgene: Tg(Tcra3A)1Skd Location: unknown
• Alliance: Tg(Tcra3A)1Skd page

Transgene origin

• Strain of Origin: SWR

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tcra3A)1Skd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)

• Mutation details: A rearranged TCR V alpha 19.1-J alpha 41 genomic clone was derived from a T helper cell clone (3A) specific for nucleosomes and its immunodominant histone peptide H4 (71- 94). (J:119333, J:119334, J:119335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:119333 Michaels MA, et al., A defect in deletion of nucleosome-specific autoimmune T cells in lupus-prone thymus: role of thymic dendritic cells. J Immunol. 2005 Nov 1;175(9):5857-65
• All: 3 reference(s)