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Rr28tm1Msb
Targeted Allele Detail
Nomenclature
Symbol: Rr28tm1Msb
Name: regulatory region 28; targeted mutation 1, Marisa S Bartolomei
MGI ID: MGI:3701074
Synonyms: H19Afp, H19tm6Msb
Gene: Rr28  Location: unknown  Genetic Position: Chr7, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118894
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert the alpha fetoprotein enhancer fragment and a floxed neomycin resistance cassette in place of the endodermal enhancers. Transient expression of cre recombinase removed the neo. (J:118894)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr28 Mutation:  0 strains or lines available
References
Original:  J:118894 Verona RI, et al., Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression. Genomics. 2004 Jul;84(1):59-68
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory