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Targeted Allele Detail
Symbol: Igltm2.1Bgmn
Name: immunoglobulin lambda chain complex; targeted mutation 2.1, Marianne Bruggemann
MGI ID: MGI:3701069
Synonyms: 1.3-2.4delta, C1-C2-C3-C4-, L-
Gene: Igl  Location: Chr16:19026858-19260844 bp, - strand  Genetic Position: Chr16, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:118712
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Allele Type:    Targeted (Null/knockout)
Mutation:    Deletion
  Igltm2.1Bgmn involves 12 genes/genome features (Igl, 2010309G21Rik, Iglc1 ...) View all
Mutation detailsLoxP insertions and cre-mediated recombination resulted in a 120Kb deletion spanning C1 through C2, and including C2 and C3. (J:118712)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igl Mutation:  0 strains or lines available
Original:  J:118712 Zou X, et al., Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain. J Immunol. 2003 Feb 1;170(3):1354-61
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory