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Targeted Allele Detail
Symbol: Dnajb1tm1Kate
Name: DnaJ heat shock protein family (Hsp40) member B1; targeted mutation 1, Kazutoyo Terada
MGI ID: MGI:3700841
Synonyms: DjB1-
Gene: Dnajb1  Location: Chr8:83608193-83612653 bp, + strand  Genetic Position: Chr8, 40.22 cM, cytoband C3
Germline Transmission:  Earliest citation of germline transmission: J:118757
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA 1.3Kb floxed neo cassette was inserted into exon 1, 40bp downstream from the initial ATG. Northern and western blot analysis of testes tissue confirmed the absence of RNA and protein expression in homozygous mice. (J:118757)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnajb1 Mutation:  8 strains or lines available
Original:  J:118757 Uchiyama Y, et al., Heat shock protein 40/DjB1 is required for thermotolerance in early phase. J Biochem. 2006 Dec;140(6):805-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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