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Apobec3Gt(XN450)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Apobec3Gt(XN450)Byg
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; gene trap XN450, BayGenomics
MGI ID: MGI:3700142
Synonyms: Apobec3-, mA3-
Gene: Apobec3  Location: Chr15:79891659-79915906 bp, + strand  Genetic Position: Chr15, 37.85 cM, cytoband E2
Mutation
origin
Mutant Cell Line:  XN450
Germline Transmission:  Earliest citation of germline transmission: J:118597
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT2Lxf     Vector Type: gene trap
    A gene trap vector containing beta-gal was inserted into intron 4 of the locus. (J:118597)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Apobec3 Mutation:  115 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:118597 Okeoma CM, et al., APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature. 2007 Feb 22;445(7130):927-30
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory