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Pclotm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Pclotm1Sud
Name: piccolo (presynaptic cytomatrix protein); targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:3699630
Synonyms: Piccolo KO
Gene: Pclo  Location: Chr5:14564932-14913473 bp, + strand  Genetic Position: Chr5, 6.27 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118451
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA targeting vector was used to flank exon 14 of the gene with loxP sites and place a neomycin cassette flanked by Frt sites in intron 14 of the gene. Mice developed from chimeras carrying the construct were crossed with a Cre deleter strain effectively removed exon 14 from the genome. (J:118451)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pclo Mutation:  165 strains or lines available
References
Original:  J:118451 Sudhof TC, Generation of a Pclo knockout mouse. MGI Direct Data Submission. 2007;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory