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Syt7tm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Syt7tm1Sud
Name: synaptotagmin VII; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:3699518
Synonyms: C2AB KI/KO
Gene: Syt7  Location: Chr19:10366454-10430544 bp, + strand  Genetic Position: Chr19, 6.58 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118318
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsPoint mutations D225A, D227A, and D233A in exon 11 (previously identified as 12), and mutations D303A, D357A, and D359A in exon 13, along with a floxed neomycin resistance gene in the intervening intron were introduced in the Syt7 locus. No protein is detected by Western blot. (J:118318, J:131423)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syt7 Mutation:  30 strains or lines available
References
Original:  J:118318 Sudhof TC, A knock-in mutation of Syt7. MGI Direct Data Submission. 2007;
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory