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Fgfr2tm2Schl
Targeted Allele Detail
Nomenclature
Symbol: Fgfr2tm2Schl
Name: fibroblast growth factor receptor 2; targeted mutation 2, Joseph Schlessinger
MGI ID: MGI:3699314
Synonyms: Fgfr2CLR, Fgfr2LR
Gene: Fgfr2  Location: Chr7:130162451-133123350 bp, - strand  Genetic Position: Chr7, 73.19 cM
Cleft palate, tracheal defects and joint analysis in Fgfr2tm1Schl/Fgfr2tm1Schl and Fgfr2tm2Schl/Fgfr2tm2Schl mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118299
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:  18 strains or lines available
References
Original:  J:118299 Eswarakumar VP, et al., Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18603-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory