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Ren1tm1Bjm
Targeted Allele Detail
Nomenclature
Symbol: Ren1tm1Bjm
Name: renin 1 structural; targeted mutation 1, Brian J Morris
MGI ID: MGI:3699140
Synonyms: REKO
Gene: Ren1  Location: Chr1:133350510-133360325 bp, + strand  Genetic Position: Chr1, 57.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117294
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting construct was designed to replace the enhancer with a floxed pgk-neo cassette that was subsequently removed via cre-mediated recombination. (J:117294)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ren1 Mutation:  24 strains or lines available
References
Original:  J:117294 Adams DJ, et al., Renin enhancer is critical for control of renin gene expression and cardiovascular function. J Biol Chem. 2006 Oct 20;281(42):31753-61
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory