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Apbb1tm1Trus
Targeted Allele Detail
Nomenclature
Symbol: Apbb1tm1Trus
Name: amyloid beta (A4) precursor protein-binding, family B, member 1; targeted mutation 1, Tommaso Russo
MGI ID: MGI:3699106
Synonyms: Fe65-, Fe65 KO
Gene: Apbb1  Location: Chr7:105558483-105581653 bp, - strand  Genetic Position: Chr7, 55.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118164
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2 was replaced with a PGK-neo cassette. (J:118164)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apbb1 Mutation:  16 strains or lines available
References
Original:  J:118164 Minopoli G, et al., Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage. J Biol Chem. 2007 Jan 12;282(2):831-5
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory