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Card9tm1Xlin
Targeted Allele Detail
Nomenclature
Symbol: Card9tm1Xlin
Name: caspase recruitment domain family, member 9; targeted mutation 1, Xin Lin
MGI ID: MGI:3698412
Synonyms: Card9-
Gene: Card9  Location: Chr2:26352176-26360918 bp, - strand  Genetic Position: Chr2, 18.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117799
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 1 was replaced with a neomycin resistance cassette in antisense orientation. Absence of transcript and protein were confirmed by RT-PCR and Western blot. (J:117799)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Card9 Mutation:  13 strains or lines available
References
Original:  J:117799 Hsu YM, et al., The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol. 2007 Feb;8(2):198-205
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory