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Apba1tm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Apba1tm1Sud
Name: amyloid beta (A4) precursor protein binding, family A, member 1; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:3697697
Gene: Apba1  Location: Chr19:23736251-23926960 bp, + strand  Genetic Position: Chr19, 18.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81845
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsFlanking loxP sites were introduced to exon 1 and an frt-flanked neomycin resistance cassette was inserted into the downstream intron via homologous recombination. (J:81845)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apba1 Mutation:  26 strains or lines available
References
Original:  J:81845 Ho A, et al., A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1409-14
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory