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Slc26a3tm1Sole
Targeted Allele Detail
Nomenclature
Symbol: Slc26a3tm1Sole
Name: solute carrier family 26, member 3; targeted mutation 1, Manoocher Soleimani
MGI ID: MGI:3697318
Synonyms: dra-
Gene: Slc26a3  Location: Chr12:31390871-31473917 bp, + strand  Genetic Position: Chr12, 13.45 cM
Colon abnormalities in Slc26a3tm1Sole/Slc26a3tm1Sole mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117587
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc26a3 Mutation:  1 strain or line available
Notes
ES cell line = TC1-10.

References
Original:  J:117587 Schweinfest CW, et al., slc26a3 (dra)-deficient mice display chloride-losing diarrhea, enhanced colonic proliferation, and distinct up-regulation of ion transporters in the colon. J Biol Chem. 2006 Dec 8;281(49):37962-71
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory