Atp1a3^tm1Ling
Targeted Allele Detail

Summary

• Symbol: Atp1a3^tm1Ling
• Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide; targeted mutation 1, Jerry B Lingrel
• MGI ID: MGI:3696954
• Synonyms: Alpha3^-
• Gene: Atp1a3 Location: Chr7:24677592-24705383 bp, - strand Genetic Position: Chr7, 13.73 cM
• Alliance: Atp1a3^tm1Ling page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117414
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Nucleotide substitutions
• Mutation details: A single base pair mutation in intron 4 adjacent to the exon-intron splice site resulted in aberrant splicing of the gene, adding 126 base pairs to the transcript. (J:117414)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp1a3 Mutation: 68 strains or lines available

References

• Original: J:117414 Moseley AE, et al., Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice. J Neurosci. 2007 Jan 17;27(3):616-26
• All: 5 reference(s)