Tg(Ckm-rtTA)102Paa
Transgene Detail

Summary

• Symbol: Tg(Ckm-rtTA)102Paa
• Name: transgene insertion 102, Parker B Antin
• MGI ID: MGI:3696944
• Synonyms: MCKrtTA, MCK-rtTA, Tg(Ckm-rtTA)1Paa
• Transgene: Tg(Ckm-rtTA)102Paa Location: unknown
• Alliance: Tg(Ckm-rtTA)102Paa page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F1

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: A transgenic construct was generated in which the codon optimized reverse tetracycline transactivator (rtTA) was placed under control of a skeletal muscle-specific version of the mouse muscle creatine kinase (Ckm) promoter. RT-PCR analysis showed that transgenic mice containing this construct expressed rtTA almost exclusively in skeletal muscles. (J:118351)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:118351 Grill MA, et al., Tetracycline-inducible system for regulation of skeletal muscle-specific gene expression in transgenic mice. Transgenic Res. 2003 Feb;12(1):33-43
• All: 8 reference(s)