Pomc^tm1Mws
Targeted Allele Detail

Summary

• Symbol: Pomc^tm1Mws
• Name: pro-opiomelanocortin-alpha; targeted mutation 1, Mark W Sleeman
• MGI ID: MGI:3696749
• Synonyms: POMC-lacZ
• Gene: Pomc Location: Chr12:4004951-4010642 bp, + strand Genetic Position: Chr12, 1.99 cM
• Alliance: Pomc^tm1Mws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117213
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• This allele contains a lacZ reporter. (J:117213)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pomc Mutation: 24 strains or lines available

References

• Original: J:117213 Munzberg H, et al., Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling. J Neurosci. 2007 Jan 3;27(1):69-74
• All: 1 reference(s)